Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α5β1 integrin towards choleresis.
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| Title: | Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α |
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| Authors: | Bonus M; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Sommerfeld A; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Qvartskhava N; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Görg B; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Ludwig BS; Institute for Advanced Study and Center for Integrated Protein Science, Department of Chemistry, Technische Universität München, Garching, Germany., Kessler H; Institute for Advanced Study and Center for Integrated Protein Science, Department of Chemistry, Technische Universität München, Garching, Germany., Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. gohlke@uni-duesseldorf.de.; John von Neumann Institute for Computing (NIC), Jülich Supercomputing Centre (JSC), and Institute for Complex Systems - Structural Biochemistry (ICS-6), Forschungszentrum Jülich GmbH, Jülich, Germany. gohlke@uni-duesseldorf.de., Häussinger D; Clinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. haeussin@uni-duesseldorf.de. |
| Source: | Scientific reports [Sci Rep] 2020 Apr 02; Vol. 10 (1), pp. 5795. Date of Electronic Publication: 2020 Apr 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-020-62326-y |
