Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.
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| Title: | Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions. |
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| Authors: | Thompson O; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., von Meyenn F; Epigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.; Department of Medical & Molecular Genetics, King's College London, London, SE1 9RT, UK.; Institute of Food, Nutrition and Health, ETH Zurich, 8603, Schwerzenbach, Switzerland., Hewitt Z; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Alexander J; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK., Wood A; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Weightman R; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Gregory S; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Krueger F; Bioinformatics Group, Babraham Institute, Cambridge, CB22 3AT, UK., Andrews S; Bioinformatics Group, Babraham Institute, Cambridge, CB22 3AT, UK., Barbaric I; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Gokhale PJ; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Moore HD; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Reik W; Epigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Milo M; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Nik-Zainal S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Academic Laboratory of Medical Genetics, Cambridge University Hospitals NHS Foundation Trust, Box 238, Lv6 Addenbrooke' Treatment Centre, Cambridge Biomedical Research Campus, Cambridge, CB2 0QQ, UK.; MRC Cancer Unit, University of Cambridge, Hutchinson/MRC Research Centre, Box 1297, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK., Yusa K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. k.yusa@infront.kyoto-u.ac.jp.; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan. k.yusa@infront.kyoto-u.ac.jp., Andrews PW; The Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK. p.w.andrews@sheffield.ac.uk. |
| Source: | Nature communications [Nat Commun] 2020 Mar 23; Vol. 11 (1), pp. 1528. Date of Electronic Publication: 2020 Mar 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-15271-3 |