The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss.
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| Title: | The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss. |
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| Authors: | Setty BA; Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, Ohio, United States of America.; Department of Pediatrics, The Ohio State University Wexner Medical Center Columbus, Ohio, United States of America., Jinesh GG; Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Florida, United States of America., Arnold M; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States of America.; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America., Pettersson F; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, United States of America., Cheng CH; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, United States of America., Cen L; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, United States of America., Yoder SJ; Molecular Genomics Core Facility, Moffitt Cancer Center, Tampa, Florida, United States of America., Teer JK; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, United States of America., Flores ER; Department of Molecular Oncology, Moffitt Cancer Center, Tampa, Florida, United States of America., Reed DR; Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Florida, United States of America.; Adolescent and Young Adult Program, Moffitt Cancer Center, Tampa, Florida, United States of America.; Sarcoma Department, Moffitt Cancer Center, Tampa, Florida, United States of America., Brohl AS; Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center, Florida, United States of America.; Sarcoma Department, Moffitt Cancer Center, Tampa, Florida, United States of America. |
| Source: | PLoS genetics [PLoS Genet] 2020 Apr 20; Vol. 16 (4), pp. e1008642. Date of Electronic Publication: 2020 Apr 20 (Print Publication: 2020). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7404 |
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| DOI: | 10.1371/journal.pgen.1008642 |
