Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis.
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| Title: | Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. |
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| Authors: | Vanneste M; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States., Feddersen CR; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Varzavand A; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA, United States., Zhu EY; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Foley T; Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Zhao L; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States., Holt KH; Viral Vector Core Facility, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Milhem M; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Piper R; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Stipp CS; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Dupuy AJ; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Henry MD; Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States.; Department of Radiation Oncology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States.; Department of Urology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA, United States. |
| Source: | Frontiers in oncology [Front Oncol] 2020 Apr 03; Vol. 10, pp. 442. Date of Electronic Publication: 2020 Apr 03 (Print Publication: 2020). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2234-943X |
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| DOI: | 10.3389/fonc.2020.00442 |
