Chemoinformatic-Guided Engineering of Polyketide Synthases.
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| Title: | Chemoinformatic-Guided Engineering of Polyketide Synthases. |
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| Authors: | Zargar A; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; QB3 Institute, University of California-Berkeley, 5885 Hollis Street, Fourth Floor, Emeryville, California 94608, United States., Lal R; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Valencia L; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Wang J; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Backman TWH; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Cruz-Morales P; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Kothari A; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Werts M; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Wong AR; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Bailey CB; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; QB3 Institute, University of California-Berkeley, 5885 Hollis Street, Fourth Floor, Emeryville, California 94608, United States., Loubat A; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Liu Y; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Chen Y; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Chang S; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Benites VT; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; Department of Energy, Agile BioFoundry, Emeryville, California 94608, United States., Hernández AC; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Barajas JF; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; Department of Energy, Agile BioFoundry, Emeryville, California 94608, United States., Thompson MG; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Barcelos C; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Anayah R; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Martin HG; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; Department of Energy, Agile BioFoundry, Emeryville, California 94608, United States.; BCAM, Basque Center for Applied Mathematics, 48009 Bilbao, Spain., Mukhopadhyay A; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States., Petzold CJ; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; Department of Energy, Agile BioFoundry, Emeryville, California 94608, United States., Baidoo EEK; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; Department of Energy, Agile BioFoundry, Emeryville, California 94608, United States., Katz L; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; QB3 Institute, University of California-Berkeley, 5885 Hollis Street, Fourth Floor, Emeryville, California 94608, United States., Keasling JD; Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Emeryville, California 94608, United States.; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94710, United States.; QB3 Institute, University of California-Berkeley, 5885 Hollis Street, Fourth Floor, Emeryville, California 94608, United States.; Department of Chemical & Biomolecular Engineering, University of California, Berkeley, California 94720, United States.; Department of Bioengineering, University of California, Berkeley, California 94720, United States.; Novo Nordisk Foundation Center for Biosustainability, Technical University Denmark, DK2970 Horsholm, Denmark.; Synthetic Biochemistry Center, Institute for Synthetic Biology, Shenzhen Institutes for Advanced Technologies, 518055 Shenzhen, China. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2020 Jun 03; Vol. 142 (22), pp. 9896-9901. Date of Electronic Publication: 2020 May 18. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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