A Broad Spectrum Chemokine Inhibitor Prevents Preterm Labor but Not Microbial Invasion of the Amniotic Cavity or Neonatal Morbidity in a Non-human Primate Model.

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Title: A Broad Spectrum Chemokine Inhibitor Prevents Preterm Labor but Not Microbial Invasion of the Amniotic Cavity or Neonatal Morbidity in a Non-human Primate Model.
Authors: Coleman M; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States., Orvis A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States., Wu TY; Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, United States., Dacanay M; Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, United States., Merillat S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States., Ogle J; Washington National Primate Center, University of Washington, Seattle, WA, United States., Baldessari A; Washington National Primate Center, University of Washington, Seattle, WA, United States., Kretzer NM; Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, United States., Munson J; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States., Boros-Rausch AJ; Department of Physiology, University of Toronto, Toronto, ON, Canada., Shynlova O; Department of Physiology, University of Toronto, Toronto, ON, Canada.; Department of Obstetrics & Gynaecology, University of Toronto, Toronto, ON, Canada., Lye S; Department of Physiology, University of Toronto, Toronto, ON, Canada.; Department of Obstetrics & Gynaecology, University of Toronto, Toronto, ON, Canada., Rajagopal L; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.; Department of Global Health, University of Washington, Seattle, WA, United States., Adams Waldorf KM; Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, United States.; Department of Global Health, University of Washington, Seattle, WA, United States.
Source: Frontiers in immunology [Front Immunol] 2020 Apr 30; Vol. 11, pp. 770. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2020.00770