MHC-I genotype and tumor mutational burden predict response to immunotherapy.
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| Title: | MHC-I genotype and tumor mutational burden predict response to immunotherapy. |
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| Authors: | Goodman AM; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA. a1goodman@ucsd.edu., Castro A; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; Health Science, Department of Biomedical Informatics, School of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA., Pyke RM; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA., Okamura R; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Kato S; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA., Riviere P; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Frampton G; Foundation Medicine, Cambridge, MA, 02141, USA., Sokol E; Foundation Medicine, Cambridge, MA, 02141, USA., Zhang X; Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, 92093, USA., Ball ED; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA., Carter H; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; CIFAR, MaRS Centre, West Tower, 661 University Ave., Suite 505, Toronto, ON, M5G 1M1, Canada., Kurzrock R; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA. |
| Source: | Genome medicine [Genome Med] 2020 May 19; Vol. 12 (1), pp. 45. Date of Electronic Publication: 2020 May 19. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1756-994X |
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| DOI: | 10.1186/s13073-020-00743-4 |
