MHC-I genotype and tumor mutational burden predict response to immunotherapy.

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Title: MHC-I genotype and tumor mutational burden predict response to immunotherapy.
Authors: Goodman AM; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA. a1goodman@ucsd.edu., Castro A; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; Health Science, Department of Biomedical Informatics, School of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA., Pyke RM; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA., Okamura R; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Kato S; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA., Riviere P; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Frampton G; Foundation Medicine, Cambridge, MA, 02141, USA., Sokol E; Foundation Medicine, Cambridge, MA, 02141, USA., Zhang X; Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, 92093, USA., Ball ED; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA., Carter H; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; CIFAR, MaRS Centre, West Tower, 661 University Ave., Suite 505, Toronto, ON, M5G 1M1, Canada., Kurzrock R; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA.
Source: Genome medicine [Genome Med] 2020 May 19; Vol. 12 (1), pp. 45. Date of Electronic Publication: 2020 May 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MHC-I genotype and tumor mutational burden predict response to immunotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Goodman+AM%22">Goodman AM</searchLink>; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA. a1goodman@ucsd.edu.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA. a1goodman@ucsd.edu.<br /><searchLink fieldCode="AU" term="%22Castro+A%22">Castro A</searchLink>; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; Health Science, Department of Biomedical Informatics, School of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Pyke+RM%22">Pyke RM</searchLink>; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Okamura+R%22">Okamura R</searchLink>; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Kato+S%22">Kato S</searchLink>; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA.<br /><searchLink fieldCode="AU" term="%22Riviere+P%22">Riviere P</searchLink>; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Frampton+G%22">Frampton G</searchLink>; Foundation Medicine, Cambridge, MA, 02141, USA.<br /><searchLink fieldCode="AU" term="%22Sokol+E%22">Sokol E</searchLink>; Foundation Medicine, Cambridge, MA, 02141, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Division of Biostatistics and Bioinformatics, Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, 92093, USA.<br /><searchLink fieldCode="AU" term="%22Ball+ED%22">Ball ED</searchLink>; Division of Blood and Marrow Transplantation, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA.<br /><searchLink fieldCode="AU" term="%22Carter+H%22">Carter H</searchLink>; Division of Medical Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.; CIFAR, MaRS Centre, West Tower, 661 University Ave., Suite 505, Toronto, ON, M5G 1M1, Canada.<br /><searchLink fieldCode="AU" term="%22Kurzrock+R%22">Kurzrock R</searchLink>; Division of Hematology/Oncology Center for Personalized Cancer Therapy, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego Moores Cancer Center, 855 Health Sciences Drive, La Jolla, CA, 92093-0658, USA.
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  Data: <searchLink fieldCode="JN" term="%22101475844%22">Genome medicine</searchLink> [Genome Med] 2020 May 19; Vol. 12 (1), pp. 45. <i>Date of Electronic Publication: </i>2020 May 19.
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