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A simple method for determining compound affinity and chemical yield from DNA-encoded library selections.

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Title: A simple method for determining compound affinity and chemical yield from DNA-encoded library selections.
Authors: Hall J; Structural Biology, Pfizer, 3200 Walnut Rd, Boulder, CO, 80301, USA. Electronic address: justin.hall@pfizer.com., Foley TL; Discovery Sciences, Pfizer, Eastern Point Rd, Groton, CT, 06340, USA., Chen Q; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China., Israel DI; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China., Xu Y; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China., Ford KK; Discovery Sciences, Pfizer, Eastern Point Rd, Groton, CT, 06340, USA., Xie P; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China., Fan J; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China., Wan J; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.
Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 18; Vol. 527 (1), pp. 250-256. Date of Electronic Publication: 2020 May 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A simple method for determining compound affinity and chemical yield from DNA-encoded library selections.
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  Data: <searchLink fieldCode="AU" term="%22Hall+J%22">Hall J</searchLink>; Structural Biology, Pfizer, 3200 Walnut Rd, Boulder, CO, 80301, USA. Electronic address: justin.hall@pfizer.com.<br /><searchLink fieldCode="AU" term="%22Foley+TL%22">Foley TL</searchLink>; Discovery Sciences, Pfizer, Eastern Point Rd, Groton, CT, 06340, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Israel+DI%22">Israel DI</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Ford+KK%22">Ford KK</searchLink>; Discovery Sciences, Pfizer, Eastern Point Rd, Groton, CT, 06340, USA.<br /><searchLink fieldCode="AU" term="%22Xie+P%22">Xie P</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Fan+J%22">Fan J</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; Lead Generation Unit, HitGen Inc, Building 6, Tianfu International Bio-Town, No. 8, Huigu 1st East Road, Shuangliu District, Chengdu, Sichuan, 610000, China.
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  Data: <searchLink fieldCode="JN" term="%220372516%22">Biochemical and biophysical research communications</searchLink> [Biochem Biophys Res Commun] 2020 Jun 18; Vol. 527 (1), pp. 250-256. <i>Date of Electronic Publication: </i>2020 May 04.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372516 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2104 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220006291X%22">0006291X </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Res Commun <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbrc.2020.04.024
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        Text: English
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              Text: 2020 Jun 18
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