Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19.

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Title: Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19.
Authors: Casey JD; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine., Johnson NJ; Department of Emergency Medicine.; Division of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and., Semler MW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine., Collins SP; Department of Emergency Medicine, and., Aggarwal NR; Division of Lung Diseases, National Heart, Lung and Blood Institute, Bethesda, Maryland., Brower RG; Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland., Chang SY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California., Eppensteiner J; Department of Surgery, Duke University, Durham, North Carolina., Filbin M; Department of Emergency Medicine., Gibbs KW; Section of Pulmonary, Critical Care, Allergy and Immunologic Disease, Department of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina., Ginde AA; Department of Emergency Medicine and., Gong MN; Division of Epidemiology and Population Health, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, New York City, New York., Harrell F; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee., Hayden DL; Department of Medicine, and., Hough CL; Division of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and., Khan A; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Oregon Health and Science University School of Medicine, Portland, Oregon., Leither LM; Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center and University of Utah, Salt Lake City, Utah., Moss M; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, Colorado., Oldmixon CF; Department of Medicine, and., Park PK; Department of Surgery, University of Michigan, Ann Arbor, Michigan., Reineck LA; Division of Lung Diseases, National Heart, Lung and Blood Institute, Bethesda, Maryland., Ringwood NJ; Department of Medicine, and., Robinson BRH; Department of Surgery, University of Washington, Seattle, Washington., Schoenfeld DA; Department of Medicine, and., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Steingrub JS; Department of Medicine, University of Massachusetts Medical School-Baystate, Springfield, Massachusetts., Torr DK; Department of Pharmacy Services, Vanderbilt University Medical Center, Nashville, Tennessee; and., Weissman A; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Lindsell CJ; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee., Rice TW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine., Thompson BT; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Brown SM; Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center and University of Utah, Salt Lake City, Utah., Self WH; Department of Emergency Medicine, and.
Source: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2020 Sep; Vol. 17 (9), pp. 1144-1153.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Clinical Trial Protocol
Journal Info: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2325-6621
DOI:10.1513/AnnalsATS.202005-478SD