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Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

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Title: Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Authors: Kung PP; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Bingham P; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Burke BJ; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Chen Q; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Cheng X; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Deng YL; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Dou D; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Feng J; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Gallego GM; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Gehring MR; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Grant SK; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Greasley S; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Harris AR; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Maegley KA; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Meier J; Chemical Biology Laboratory, National Cancer Institute, Frederick, Maryland 21702, United States., Meng X; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Montano JL; Chemical Biology Laboratory, National Cancer Institute, Frederick, Maryland 21702, United States., Morgan BA; HitGen Pharmaceuticals Inc., PO Box 88240, Houston, Texas 77288, United States.; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Naughton BS; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Palde PB; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Paul TA; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Richardson P; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Sakata S; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Shaginian A; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Sonnenburg WK; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Subramanyam C; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Timofeevski S; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Wan J; HitGen Inc., Building 6, No.8, Huigu first East Road, Tianfu International Bio-Town, Shuangliu District, Chengdu, Sichuan 610200, P.R. China., Yan W; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States., Stewart AE; Worldwide Research and Development, Pfizer Inc., 10770 Science Center Drive, San Diego, California 92121, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Apr 10; Vol. 11 (6), pp. 1175-1184. Date of Electronic Publication: 2020 Apr 10 (Print Publication: 2020).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1948-5875
DOI:10.1021/acsmedchemlett.0c00029