Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.

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Title: Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Authors: Abdelrasoul H; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Vadakumchery A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Werner M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Lenk L; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Khadour A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Young M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., El Ayoubi O; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Vogiatzi F; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Krämer M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Schmid V; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Chen Z; Department of Systems Biology and City of Hope Comprehensive Cancer Center, Monrovia, CA, USA., Yousafzai Y; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Cario G; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Schrappe M; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Müschen M; Department of Systems Biology and City of Hope Comprehensive Cancer Center, Monrovia, CA, USA., Halsey C; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Mulaw MA; Institute of Experimental Cancer Research, Medical Faculty, University of Ulm, Ulm, Germany., Schewe DM; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Hobeika E; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Alsadeq A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany., Jumaa H; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany. hassan.jumaa@uni-ulm.de.
Source: Nature communications [Nat Commun] 2020 Jun 24; Vol. 11 (1), pp. 3194. Date of Electronic Publication: 2020 Jun 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-020-16927-w