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A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.

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Title: A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.
Authors: Ray D; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore; debleena.ray@duke-nus.edu.sg david.epstein@duke-nus.edu.sg., Yun YC; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore., Idris M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore., Cheng S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore., Boot A; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore., Iain TBH; Division of Medical Oncology, National Cancer Centre, 169610 Singapore, Singapore., Rozen SG; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore., Tan P; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore., Epstein DM; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore; debleena.ray@duke-nus.edu.sg david.epstein@duke-nus.edu.sg.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 14; Vol. 117 (28), pp. 16391-16400. Date of Electronic Publication: 2020 Jun 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.
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  Data: <searchLink fieldCode="AU" term="%22Ray+D%22">Ray D</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore; debleena.ray@duke-nus.edu.sg david.epstein@duke-nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Yun+YC%22">Yun YC</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Idris+M%22">Idris M</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheng+S%22">Cheng S</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Boot+A%22">Boot A</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Iain+TBH%22">Iain TBH</searchLink>; Division of Medical Oncology, National Cancer Centre, 169610 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Rozen+SG%22">Rozen SG</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Epstein+DM%22">Epstein DM</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore; debleena.ray@duke-nus.edu.sg david.epstein@duke-nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2020 Jul 14; Vol. 117 (28), pp. 16391-16400. <i>Date of Electronic Publication: </i>2020 Jun 29.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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        Value: 10.1073/pnas.2002499117
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        Text: English
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              Text: 2020 Jul 14
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