Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.

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Bibliographic Details
Title: Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
Authors: Takahashi K; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Akatsu Y; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.; Biomedicine Group, Pharmaceutical Research Laboratories, and Pharmaceutical Group, Nippon Kayaku Co. Ltd., Tokyo, Japan., Podyma-Inoue KA; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Matsumoto T; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan., Takahashi H; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Yoshimatsu Y; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.; Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Koinuma D; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Shirouzu M; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan., Miyazono K; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Watabe T; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan t-watabe@umin.ac.jp.
Source: The Journal of biological chemistry [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12559-12572. Date of Electronic Publication: 2020 Jul 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1074/jbc.RA120.012492