Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.

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Title: Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Authors: Yurkovetskiy L; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.; These authors contributed equally to this work., Wang X; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands.; These authors contributed equally to this work., Pascal KE; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591., Tomkins-Tinch C; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA.; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA., Nyalile T; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Wang Y; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Baum A; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591., Diehl WE; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Dauphin A; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Carbone C; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Veinotte K; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Egri SB; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Schaffner SF; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA.; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA., Lemieux JE; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA.; Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114., Munro J; D epartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605, USA.; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA., Rafique A; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591., Barve A; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands., Sabeti PC; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA.; Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.; Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, 02115 Boston, MA.; Howard Hughes Medical Institute, 4000 Jones Bridge Rd, Chevy Chase, MD 20815.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115., Kyratsous CA; Regeneron Pharmaceutical, Inc., 777 Old Saw Mill River Rd, Tarrytown, NY 10591., Dudkina N; Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG Eindhoven, Netherlands., Shen K; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Luban J; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.; Broad Institute of Harvard and MIT, 75 Ames Street, Cambridge, MA 02142, USA.; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, 02115.; Lead contact.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2020 Jul 15. Date of Electronic Publication: 2020 Jul 15.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2020.07.04.187757