The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function.
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| Title: | The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function. |
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| Authors: | Bennett JA; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Mastrangelo MA; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Ture SK; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Smith CO; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY, 14642, USA., Loelius SG; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642, USA., Berg RA; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Shi X; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Burke RM; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Spinelli SL; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Cameron SJ; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Carey TE; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA., Brookes PS; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY, 14642, USA., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.; Genomics of Complex Diseases, Research Institute of Hospital de la Santa Creu i Sant Pau (IIB Sant Pau), Barcelona, Spain., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Huffman JE; Center for Population Genomics, MAVERIC, VA Boston Healthcare System, Jamaica Plain, MA, USA., Smith NL; Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA, USA., Morrell CN; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA., Lowenstein CJ; Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA. clowens1@jhmi.edu. |
| Source: | Nature communications [Nat Commun] 2020 Jul 13; Vol. 11 (1), pp. 3479. Date of Electronic Publication: 2020 Jul 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-17254-w |
