Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss.
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| Title: | Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss. |
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| Authors: | Dobson PF; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Dennis EP; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Hipps D; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Reeve A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Laude A; Bioimaging Unit, Medical School, FMS Professional Services, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Bradshaw C; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Stamp C; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Smith A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Deehan DJ; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Turnbull DM; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. doug.turnbull@ncl.ac.uk.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. doug.turnbull@ncl.ac.uk., Greaves LC; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. laura.greaves@ncl.ac.uk.; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. laura.greaves@ncl.ac.uk. |
| Source: | Scientific reports [Sci Rep] 2020 Jul 15; Vol. 10 (1), pp. 11643. Date of Electronic Publication: 2020 Jul 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-020-68566-2 |