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Fasting-mimicking diet and hormone therapy induce breast cancer regression.

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Title: Fasting-mimicking diet and hormone therapy induce breast cancer regression.
Authors: Caffa I; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Spagnolo V; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy., Vernieri C; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.; Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Valdemarin F; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Becherini P; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Wei M; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA., Brandhorst S; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA., Zucal C; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Driehuis E; Oncode Institute and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands., Ferrando L; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Piacente F; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Tagliafico A; Department of Health Sciences, University of Genoa, Genoa, Italy., Cilli M; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Mastracci L; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Integrated Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy., Vellone VG; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Integrated Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy., Piazza S; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Cremonini AL; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Gradaschi R; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Mantero C; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Passalacqua M; Department of Experimental Medicine, University of Genoa, Genoa, Italy., Ballestrero A; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Zoppoli G; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Cea M; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Arrighi A; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Odetti P; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Monacelli F; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Salvadori G; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy., Cortellino S; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy., Clevers H; Oncode Institute and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands., De Braud F; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Sukkar SG; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Provenzani A; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy., Longo VD; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy. vlongo@usc.edu.; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA. vlongo@usc.edu., Nencioni A; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. alessio.nencioni@unige.it.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy. alessio.nencioni@unige.it.
Source: Nature [Nature] 2020 Jul; Vol. 583 (7817), pp. 620-624. Date of Electronic Publication: 2020 Jul 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Fasting-mimicking diet and hormone therapy induce breast cancer regression.
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  Data: <searchLink fieldCode="AU" term="%22Caffa+I%22">Caffa I</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Spagnolo+V%22">Spagnolo V</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vernieri+C%22">Vernieri C</searchLink>; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.; Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Valdemarin+F%22">Valdemarin F</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Becherini+P%22">Becherini P</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Wei+M%22">Wei M</searchLink>; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brandhorst+S%22">Brandhorst S</searchLink>; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zucal+C%22">Zucal C</searchLink>; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Driehuis+E%22">Driehuis E</searchLink>; Oncode Institute and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ferrando+L%22">Ferrando L</searchLink>; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Piacente+F%22">Piacente F</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Tagliafico+A%22">Tagliafico A</searchLink>; Department of Health Sciences, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Cilli+M%22">Cilli M</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Mastracci+L%22">Mastracci L</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Integrated Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Vellone+VG%22">Vellone VG</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Integrated Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Piazza+S%22">Piazza S</searchLink>; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Cremonini+AL%22">Cremonini AL</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Gradaschi+R%22">Gradaschi R</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Mantero+C%22">Mantero C</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Passalacqua+M%22">Passalacqua M</searchLink>; Department of Experimental Medicine, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Ballestrero+A%22">Ballestrero A</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Zoppoli+G%22">Zoppoli G</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Cea+M%22">Cea M</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Arrighi+A%22">Arrighi A</searchLink>; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Odetti+P%22">Odetti P</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Monacelli+F%22">Monacelli F</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Salvadori+G%22">Salvadori G</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cortellino+S%22">Cortellino S</searchLink>; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Clevers+H%22">Clevers H</searchLink>; Oncode Institute and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22De+Braud+F%22">De Braud F</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.; Medical Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sukkar+SG%22">Sukkar SG</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Provenzani+A%22">Provenzani A</searchLink>; Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Longo+VD%22">Longo VD</searchLink>; IFOM, FIRC Institute of Molecular Oncology, Milan, Italy. vlongo@usc.edu.; Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA. vlongo@usc.edu.<br /><searchLink fieldCode="AU" term="%22Nencioni+A%22">Nencioni A</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. alessio.nencioni@unige.it.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy. alessio.nencioni@unige.it.
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