Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.

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Title: Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
Authors: Hagenaars SP; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK., Coleman JRI; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK., Choi SW; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Gaspar H; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK., Adams MJ; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Howard DM; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Hodgson K; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK., Traylor M; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK., Air TM; Discipline of Medicine, University of Adelaide, Adelaide, Australia., Andlauer TFM; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Arolt V; Department of Psychiatry, University of Münster, Münster, Germany., Baune BT; Department of Psychiatry, University of Münster, Münster, Germany.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Australia.; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia., Binder EB; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA., Blackwood DHR; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Boomsma DI; Netherlands Twin Register, Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, The Netherlands., Campbell A; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Cearns M; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Australia., Czamara D; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany., Dannlowski U; Department of Psychiatry, University of Münster, Münster, Germany., Domschke K; Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany., de Geus EJC; Netherlands Twin Register, Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, The Netherlands., Hamilton SP; Department of Psychiatry, Kaiser Permanente Northern California, San Francisco, California, USA., Hayward C; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hickie IB; Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia., Hottenga JJ; Netherlands Twin Register, Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, The Netherlands., Ising M; Max Planck Institute of Psychiatry, Munich, Germany., Jones I; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Jones L; Department of Psychological Medicine, University of Worcester, Worcester, UK., Kutalik Z; Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lucae S; Max Planck Institute of Psychiatry, Munich, Germany., Martin NG; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience Research Institutes, Amsterdam UMC/Vrije Universiteit, Amsterdam, The Netherlands., Mueller-Myhsok B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, UK., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience Research Institutes, Amsterdam UMC/Vrije Universiteit, Amsterdam, The Netherlands., Pistis G; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Porteous DJ; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Preisig M; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Psychiatry and Psychotherapy, Universitätsmedizin Berlin Campus Charité Mitte, Berlin, Maryland, USA.; Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA., Shyn SI; Behavioral Health Services, Kaiser Permanente Washington, Seattle, Washington, USA., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Whitfield JB; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Wray NR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Breen G; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK., Lewis CM; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK.
Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [Am J Med Genet B Neuropsychiatr Genet] 2020 Sep; Vol. 183 (6), pp. 309-330. Date of Electronic Publication: 2020 Jul 18.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-485X (Electronic) Linking ISSN: 15524841 NLM ISO Abbreviation: Am J Med Genet B Neuropsychiatr Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1552-485X
DOI:10.1002/ajmg.b.32807