Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.

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Title: Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Authors: Hsieh CL; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Goldsmith JA; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Schaub JM; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., DiVenere AM; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA., Kuo HC; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Javanmardi K; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Le KC; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA., Wrapp D; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Lee AG; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Liu Y; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA., Chou CW; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Byrne PO; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Hjorth CK; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Johnson NV; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Ludes-Meyers J; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Nguyen AW; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA., Park J; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Wang N; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Amengor D; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA., Lavinder JJ; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA.; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA., Ippolito GC; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA.; Department of Oncology, Dell Medical School, University of Texas, Austin, TX 78712, USA., Maynard JA; Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA. maynard@che.utexas.edu ilya@finkelsteinlab.org jmclellan@austin.utexas.edu., Finkelstein IJ; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA. maynard@che.utexas.edu ilya@finkelsteinlab.org jmclellan@austin.utexas.edu.; Center for Systems and Synthetic Biology, University of Texas, Austin, TX 78712, USA., McLellan JS; Department of Molecular Biosciences, University of Texas, Austin, TX 78712, USA. maynard@che.utexas.edu ilya@finkelsteinlab.org jmclellan@austin.utexas.edu.
Source: Science (New York, N.Y.) [Science] 2020 Sep 18; Vol. 369 (6510), pp. 1501-1505. Date of Electronic Publication: 2020 Jul 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.abd0826