Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
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| Title: | Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs. |
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| Authors: | Wilbs J; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Kong XD; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Middendorp SJ; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Prince R; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.; Department of Clinical Research, University of Bern, CH-3008, Bern, Switzerland., Cooke A; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Demarest CT; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Abdelhafez MM; Department of Clinical Research, University of Bern, CH-3008, Bern, Switzerland., Roberts K; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Umei N; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Gonschorek P; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Lamers C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Deyle K; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland., Rieben R; Department of Clinical Research, University of Bern, CH-3008, Bern, Switzerland., Cook KE; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA., Angelillo-Scherrer A; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, CH-3010, Bern, Switzerland.; Department of Clinical Research, University of Bern, CH-3008, Bern, Switzerland., Heinis C; Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland. christian.heinis@epfl.ch. |
| Source: | Nature communications [Nat Commun] 2020 Aug 04; Vol. 11 (1), pp. 3890. Date of Electronic Publication: 2020 Aug 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-020-17648-w |
