Genome-wide analysis of single nucleotide variants allows for robust and accurate assessment of clonal derivation in cell lines used to produce biologics.
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| Title: | Genome-wide analysis of single nucleotide variants allows for robust and accurate assessment of clonal derivation in cell lines used to produce biologics. |
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| Authors: | Kuhn A; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Switzerland.; Selexis SA, Geneva, Switzerland., Le Fourn V; Selexis SA, Geneva, Switzerland., Fisch I; Selexis SA, Geneva, Switzerland., Mermod N; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, Switzerland. |
| Source: | Biotechnology and bioengineering [Biotechnol Bioeng] 2020 Dec; Vol. 117 (12), pp. 3628-3638. Date of Electronic Publication: 2020 Aug 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0290 |
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| DOI: | 10.1002/bit.27534 |
