Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates.
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| Title: | Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. |
|---|---|
| Authors: | Brown CR; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Gupta S; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Qin J; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Racie T; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., He G; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Lentini S; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Malone R; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Yu M; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Matsuda S; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Shulga-Morskaya S; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Nair AV; MGH Program in Membrane Biology, Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Theile CS; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Schmidt K; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Shahraz A; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Goel V; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Parmar RG; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Zlatev I; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Schlegel MK; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Nair JK; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Jayaraman M; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Manoharan M; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Brown D; MGH Program in Membrane Biology, Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Maier MA; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA., Jadhav V; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11827-11844. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 32808038 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Brown+CR%22">Brown CR</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Qin+J%22">Qin J</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Racie+T%22">Racie T</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22He+G%22">He G</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Lentini+S%22">Lentini S</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Malone+R%22">Malone R</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Yu+M%22">Yu M</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Matsuda+S%22">Matsuda S</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Shulga-Morskaya+S%22">Shulga-Morskaya S</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Nair+AV%22">Nair AV</searchLink>; MGH Program in Membrane Biology, Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Theile+CS%22">Theile CS</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+K%22">Schmidt K</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Shahraz+A%22">Shahraz A</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Goel+V%22">Goel V</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Parmar+RG%22">Parmar RG</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Zlatev+I%22">Zlatev I</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Schlegel+MK%22">Schlegel MK</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Nair+JK%22">Nair JK</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Jayaraman+M%22">Jayaraman M</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Manoharan+M%22">Manoharan M</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Brown+D%22">Brown D</searchLink>; MGH Program in Membrane Biology, Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Maier+MA%22">Maier MA</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Jadhav+V%22">Jadhav V</searchLink>; Alnylam Pharmaceuticals, Inc., Cambridge, MA 02142, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220411011%22">Nucleic acids research</searchLink> [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11827-11844. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0411011 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1362-4962 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203051048%22">03051048 </searchLink><i>NLM ISO Abbreviation: </i>Nucleic Acids Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=32808038 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/nar/gkaa670 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 11827 Titles: – TitleFull: Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Brown CR – PersonEntity: Name: NameFull: Gupta S – PersonEntity: Name: NameFull: Qin J – PersonEntity: Name: NameFull: Racie T – PersonEntity: Name: NameFull: He G – PersonEntity: Name: NameFull: Lentini S – PersonEntity: Name: NameFull: Malone R – PersonEntity: Name: NameFull: Yu M – PersonEntity: Name: NameFull: Matsuda S – PersonEntity: Name: NameFull: Shulga-Morskaya S – PersonEntity: Name: NameFull: Nair AV – PersonEntity: Name: NameFull: Theile CS – PersonEntity: Name: NameFull: Schmidt K – PersonEntity: Name: NameFull: Shahraz A – PersonEntity: Name: NameFull: Goel V – PersonEntity: Name: NameFull: Parmar RG – PersonEntity: Name: NameFull: Zlatev I – PersonEntity: Name: NameFull: Schlegel MK – PersonEntity: Name: NameFull: Nair JK – PersonEntity: Name: NameFull: Jayaraman M – PersonEntity: Name: NameFull: Manoharan M – PersonEntity: Name: NameFull: Brown D – PersonEntity: Name: NameFull: Maier MA – PersonEntity: Name: NameFull: Jadhav V IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 12 Text: 2020 Dec 02 Type: published Y: 2020 Identifiers: – Type: issn-electronic Value: 1362-4962 Numbering: – Type: volume Value: 48 – Type: issue Value: 21 Titles: – TitleFull: Nucleic acids research Type: main |
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