Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy.
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| Title: | Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy. |
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| Authors: | Schaser AJ; Department of Neurology and Jungers Center for Neurosciences Research, Oregon Health and Science University, Portland, OR, 97239, USA., Stackhouse TL; Department of Neurology and Jungers Center for Neurosciences Research, Oregon Health and Science University, Portland, OR, 97239, USA., Weston LJ; Department of Neurology and Jungers Center for Neurosciences Research, Oregon Health and Science University, Portland, OR, 97239, USA., Kerstein PC; Vollum Institute, Oregon Health and Science University, Portland, OR, 97239, USA., Osterberg VR; Department of Neurology and Jungers Center for Neurosciences Research, Oregon Health and Science University, Portland, OR, 97239, USA., López CS; Multiscale Microscopy Core, Oregon Health and Science University, Portland, OR, 97239, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Luk KC; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Meshul CK; Research Services, Veterans Affairs Medical Center, Portland, OR, 97239, USA.; Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, 97239, USA., Woltjer RL; Department of Pathology, Oregon Health and Science University, Portland, OR, 97239, USA., Unni VK; Department of Neurology and Jungers Center for Neurosciences Research, Oregon Health and Science University, Portland, OR, 97239, USA. unni@ohsu.edu.; Parkinson Center, Department of Neurology, Oregon Health and Science University, Portland, OR, 97239, USA. unni@ohsu.edu. |
| Source: | Acta neuropathologica communications [Acta Neuropathol Commun] 2020 Aug 28; Vol. 8 (1), pp. 150. Date of Electronic Publication: 2020 Aug 28. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2051-5960 |
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| DOI: | 10.1186/s40478-020-01026-0 |
