Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.

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Title: Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.
Authors: Lee LA; GlaxoSmithKline (GSK), Collegeville, PA, USA., Bailes Z; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Barnes N; GSK, Brentford, Middlesex, UK; Barts and the London School of Medicine and Dentistry, London, UK., Boulet LP; Laval University, Quebec, QC, Canada., Edwards D; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Fowler A; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Hanania NA; Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA., Kerstjens HAM; University of Groningen and University Medical Center Groningen, and Groningen Research Institute for Asthma and COPD, Groningen, Netherlands., Kerwin E; Crisor, Clinical Research Institute, Medford, OR, USA., Nathan R; Asthma & Allergy Associates, PC and Research Center, Colorado Springs, CO, USA., Oppenheimer J; Rutgers New Jersey Medical School, Newark, NJ, USA., Papi A; University of Ferrara, Ferrara, Italy., Pascoe S; GlaxoSmithKline (GSK), Collegeville, PA, USA., Brusselle G; Ghent University Hospital, Ghent, Belgium., Peachey G; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Sule N; GlaxoSmithKline (GSK), Collegeville, PA, USA., Tabberer M; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Pavord ID; Nuffield Department of Medicine and Oxford Respiratory NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address: ian.pavord@ndm.ox.ac.uk.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2021 Jan; Vol. 9 (1), pp. 69-84. Date of Electronic Publication: 2020 Sep 09.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2213-2619
DOI:10.1016/S2213-2600(20)30389-1