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Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.

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Title: Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.
Authors: Lee LA; GlaxoSmithKline (GSK), Collegeville, PA, USA., Bailes Z; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Barnes N; GSK, Brentford, Middlesex, UK; Barts and the London School of Medicine and Dentistry, London, UK., Boulet LP; Laval University, Quebec, QC, Canada., Edwards D; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Fowler A; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Hanania NA; Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA., Kerstjens HAM; University of Groningen and University Medical Center Groningen, and Groningen Research Institute for Asthma and COPD, Groningen, Netherlands., Kerwin E; Crisor, Clinical Research Institute, Medford, OR, USA., Nathan R; Asthma & Allergy Associates, PC and Research Center, Colorado Springs, CO, USA., Oppenheimer J; Rutgers New Jersey Medical School, Newark, NJ, USA., Papi A; University of Ferrara, Ferrara, Italy., Pascoe S; GlaxoSmithKline (GSK), Collegeville, PA, USA., Brusselle G; Ghent University Hospital, Ghent, Belgium., Peachey G; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Sule N; GlaxoSmithKline (GSK), Collegeville, PA, USA., Tabberer M; GSK, Stockley Park West, Uxbridge, Middlesex, UK., Pavord ID; Nuffield Department of Medicine and Oxford Respiratory NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address: ian.pavord@ndm.ox.ac.uk.
Source: The Lancet. Respiratory medicine [Lancet Respir Med] 2021 Jan; Vol. 9 (1), pp. 69-84. Date of Electronic Publication: 2020 Sep 09.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind, randomised, phase 3A trial.
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  Data: <searchLink fieldCode="AU" term="%22Lee+LA%22">Lee LA</searchLink>; GlaxoSmithKline (GSK), Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bailes+Z%22">Bailes Z</searchLink>; GSK, Stockley Park West, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Barnes+N%22">Barnes N</searchLink>; GSK, Brentford, Middlesex, UK; Barts and the London School of Medicine and Dentistry, London, UK.<br /><searchLink fieldCode="AU" term="%22Boulet+LP%22">Boulet LP</searchLink>; Laval University, Quebec, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Edwards+D%22">Edwards D</searchLink>; GSK, Stockley Park West, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Fowler+A%22">Fowler A</searchLink>; GSK, Stockley Park West, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Hanania+NA%22">Hanania NA</searchLink>; Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kerstjens+HAM%22">Kerstjens HAM</searchLink>; University of Groningen and University Medical Center Groningen, and Groningen Research Institute for Asthma and COPD, Groningen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kerwin+E%22">Kerwin E</searchLink>; Crisor, Clinical Research Institute, Medford, OR, USA.<br /><searchLink fieldCode="AU" term="%22Nathan+R%22">Nathan R</searchLink>; Asthma & Allergy Associates, PC and Research Center, Colorado Springs, CO, USA.<br /><searchLink fieldCode="AU" term="%22Oppenheimer+J%22">Oppenheimer J</searchLink>; Rutgers New Jersey Medical School, Newark, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Papi+A%22">Papi A</searchLink>; University of Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Pascoe+S%22">Pascoe S</searchLink>; GlaxoSmithKline (GSK), Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brusselle+G%22">Brusselle G</searchLink>; Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Peachey+G%22">Peachey G</searchLink>; GSK, Stockley Park West, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Sule+N%22">Sule N</searchLink>; GlaxoSmithKline (GSK), Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tabberer+M%22">Tabberer M</searchLink>; GSK, Stockley Park West, Uxbridge, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Pavord+ID%22">Pavord ID</searchLink>; Nuffield Department of Medicine and Oxford Respiratory NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address: ian.pavord@ndm.ox.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101605555%22">The Lancet. Respiratory medicine</searchLink> [Lancet Respir Med] 2021 Jan; Vol. 9 (1), pp. 69-84. <i>Date of Electronic Publication: </i>2020 Sep 09.
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  Data: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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