Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
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| Title: | Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. |
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| Authors: | Shrock E; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Fujimura E; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA.; Chemical Biology Program, Harvard University, Cambridge, MA, USA., Kula T; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Timms RT; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Lee IH; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Leng Y; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Robinson ML; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sie BM; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Li MZ; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA., Chen Y; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Logue J; Department of Medicine, University of Washington, Seattle, WA, USA., Zuiani A; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., McCulloch D; Department of Medicine, University of Washington, Seattle, WA, USA., Lelis FJN; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Henson S; Institute for Cell Engineering, Immunology Division, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Monaco DR; Institute for Cell Engineering, Immunology Division, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Travers M; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Habibi S; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Clarke WA; Division of Clinical Chemistry, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Caturegli P; Division of Immunology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Laeyendecker O; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Division of Intramural Research, NIAID, NIH, Baltimore, MD, USA., Piechocka-Trocha A; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA.; Howard Hughes Medical Institute, Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Li JZ; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA.; Infectious Disease Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Khatri A; Endocrine Unit and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Chu HY; Department of Medicine, University of Washington, Seattle, WA, USA., Villani AC; Massachusetts General Hospital Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Kays K; Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA., Goldberg MB; Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine and Microbiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Hacohen N; Massachusetts General Hospital Cancer Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Filbin MR; Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA., Yu XG; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA.; Infectious Disease Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Walker BD; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA.; Howard Hughes Medical Institute, Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.; Centre for the AIDS Programme of Research in South Africa, Congella, South Africa., Wesemann DR; Division of Allergy and Immunology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA., Larman HB; Institute for Cell Engineering, Immunology Division, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Lederer JA; Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Elledge SJ; Department of Genetics, Harvard Medical School, Boston, MA, USA. selledge@genetics.med.harvard.edu.; Howard Hughes Medical Institute, Division of Genetics, Brigham and Women's Hospital, Program in Virology, Harvard Medical School, Boston, MA, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA, USA. |
| Corporate Authors: | MGH COVID-19 Collection & Processing Team |
| Source: | Science (New York, N.Y.) [Science] 2020 Nov 27; Vol. 370 (6520). Date of Electronic Publication: 2020 Sep 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.abd4250 |
