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CART19-BE-01: A Multicenter Trial of ARI-0001 Cell Therapy in Patients with CD19+ Relapsed/Refractory Malignancies.

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Title: CART19-BE-01: A Multicenter Trial of ARI-0001 Cell Therapy in Patients with CD19+ Relapsed/Refractory Malignancies.
Authors: Ortíz-Maldonado V; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain., Rives S; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain., Castellà M; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain., Alonso-Saladrigues A; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain., Benítez-Ribas D; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain., Caballero-Baños M; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain., Baumann T; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain., Cid J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Apheresis & Cell Therapy Unit, Department of Hemotherapy and Hemostasis, Hospital Clínic de Barcelona, Barcelona, Spain., Garcia-Rey E; Banc de Sang i Teixits, Barcelona, Spain., Llanos C; Clinical Research Unit, Fundació Sant Joan de Déu, Barcelona, Spain., Torrebadell M; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain; Laboratory of Hematology, Hospital Sant Joan de Déu, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) , Barcelona, Spain., Villamor N; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Hematopathology Unit, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Giné E; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Díaz-Beyá M; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain., Guardia L; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain., Montoro M; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain., Català A; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain., Faura A; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain., González EA; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain., Español-Rego M; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain., Klein-González N; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain., Alsina L; Clinical Immunology Platform Clínic-Sant Joan de Déu, Barcelona, Spain., Castro P; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Medical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain; University of Barcelona, Barcelona, Spain., Jordan I; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain; University of Barcelona, Barcelona, Spain; Intensive Care Unit, Hospital Sant Joan de Déu, Barcelona, Spain., Fernández S; Medical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain., Ramos F; Department of Neurology, Hospital Sant Joan de Déu, Barcelona, Spain., Suñé G; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain., Perpiñá U; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Laboratory of Stem Cells and Regenerative Medicine, Department of Biomedicine, Production and Validation Center of Advanced Therapies (Creatio), University of Barcelona, Barcelona, Spain., Canals JM; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Laboratory of Stem Cells and Regenerative Medicine, Department of Biomedicine, Production and Validation Center of Advanced Therapies (Creatio), University of Barcelona, Barcelona, Spain., Lozano M; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Apheresis & Cell Therapy Unit, Department of Hemotherapy and Hemostasis, Hospital Clínic de Barcelona, Barcelona, Spain; University of Barcelona, Barcelona, Spain., Trias E; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain., Scalise A; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain., Varea S; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain., Sáez-Peñataro J; University of Barcelona, Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain., Torres F; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain., Calvo G; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain., Esteve J; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; University of Barcelona, Barcelona, Spain; Institute of Research Josep Carreras, Barcelona, Spain., Urbano-Ispizua Á; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; University of Barcelona, Barcelona, Spain; Institute of Research Josep Carreras, Barcelona, Spain., Juan M; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain; Clinical Immunology Platform Clínic-Sant Joan de Déu, Barcelona, Spain; University of Barcelona, Barcelona, Spain; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: mjuan@clinic.cat., Delgado J; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address: jdelgado@clinic.cat.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Feb 03; Vol. 29 (2), pp. 636-644. Date of Electronic Publication: 2020 Sep 20.
Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: CART19-BE-01: A Multicenter Trial of ARI-0001 Cell Therapy in Patients with CD19<superscript>+</superscript> Relapsed/Refractory Malignancies.
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  Data: <searchLink fieldCode="AU" term="%22Ortíz-Maldonado+V%22">Ortíz-Maldonado V</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rives+S%22">Rives S</searchLink>; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Castellà+M%22">Castellà M</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso-Saladrigues+A%22">Alonso-Saladrigues A</searchLink>; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Benítez-Ribas+D%22">Benítez-Ribas D</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Caballero-Baños+M%22">Caballero-Baños M</searchLink>; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Baumann+T%22">Baumann T</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cid+J%22">Cid J</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Apheresis & Cell Therapy Unit, Department of Hemotherapy and Hemostasis, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Rey+E%22">Garcia-Rey E</searchLink>; Banc de Sang i Teixits, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Llanos+C%22">Llanos C</searchLink>; Clinical Research Unit, Fundació Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Torrebadell+M%22">Torrebadell M</searchLink>; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain; Laboratory of Hematology, Hospital Sant Joan de Déu, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) , Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Villamor+N%22">Villamor N</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Hematopathology Unit, Hospital Clínic de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Giné+E%22">Giné E</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Díaz-Beyá+M%22">Díaz-Beyá M</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Guardia+L%22">Guardia L</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Montoro+M%22">Montoro M</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Català+A%22">Català A</searchLink>; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Faura+A%22">Faura A</searchLink>; Department of Hematology/Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22González+EA%22">González EA</searchLink>; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Español-Rego+M%22">Español-Rego M</searchLink>; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Klein-González+N%22">Klein-González N</searchLink>; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alsina+L%22">Alsina L</searchLink>; Clinical Immunology Platform Clínic-Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Castro+P%22">Castro P</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Medical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Jordan+I%22">Jordan I</searchLink>; Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, Spain; University of Barcelona, Barcelona, Spain; Intensive Care Unit, Hospital Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+S%22">Fernández S</searchLink>; Medical Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ramos+F%22">Ramos F</searchLink>; Department of Neurology, Hospital Sant Joan de Déu, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Suñé+G%22">Suñé G</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Perpiñá+U%22">Perpiñá U</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Laboratory of Stem Cells and Regenerative Medicine, Department of Biomedicine, Production and Validation Center of Advanced Therapies (Creatio), University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Canals+JM%22">Canals JM</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Laboratory of Stem Cells and Regenerative Medicine, Department of Biomedicine, Production and Validation Center of Advanced Therapies (Creatio), University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lozano+M%22">Lozano M</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Apheresis & Cell Therapy Unit, Department of Hemotherapy and Hemostasis, Hospital Clínic de Barcelona, Barcelona, Spain; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Trias+E%22">Trias E</searchLink>; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Scalise+A%22">Scalise A</searchLink>; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Varea+S%22">Varea S</searchLink>; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sáez-Peñataro+J%22">Sáez-Peñataro J</searchLink>; University of Barcelona, Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Torres+F%22">Torres F</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Calvo+G%22">Calvo G</searchLink>; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain; Department of Pharmacology, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Esteve+J%22">Esteve J</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; University of Barcelona, Barcelona, Spain; Institute of Research Josep Carreras, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Urbano-Ispizua+Á%22">Urbano-Ispizua Á</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; University of Barcelona, Barcelona, Spain; Institute of Research Josep Carreras, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Juan+M%22">Juan M</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Department of Immunology, Hospital Clínic de Barcelona, Barcelona, Spain; Clinical Immunology Platform Clínic-Sant Joan de Déu, Barcelona, Spain; University of Barcelona, Barcelona, Spain; Advanced Therapies Unit, Hospital Clínic de Barcelona, Barcelona, Spain. Electronic address: mjuan@clinic.cat.<br /><searchLink fieldCode="AU" term="%22Delgado+J%22">Delgado J</searchLink>; Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address: jdelgado@clinic.cat.
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