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FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.

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Title: FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
Authors: Zaghdoudi S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Decaup E; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Belhabib I; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Samain R; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Cassant-Sourdy S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Rochotte J; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Brunel A; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Schlaepfer D; Department of Reproductive Medicine Moores Cancer Center, University of California San Diego, La Jolla, CA, USA., Cros J; Department of Pathology, Beaujon Hospital, INSERM U1149, Clichy, France., Neuzillet C; Medical Oncology Department, Curie Institute, Versailles Saint-Quentin University, Saint-Cloud, France., Strehaiano M; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Alard A; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Tomasini R; Cancer Research Center of Marseille, INSERM U1068, Marseille, France., Rajeeve V; Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK., Perraud A; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France., Mathonnet M; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France., Pearce OM; Centre for Tumour Microenvironment, Barts Cancer Institute, London, UK., Martineau Y; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Pyronnet S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Bousquet C; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Jean C; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.
Source: EMBO molecular medicine [EMBO Mol Med] 2020 Nov 06; Vol. 12 (11), pp. e12010. Date of Electronic Publication: 2020 Oct 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1757-4684
DOI:10.15252/emmm.202012010