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FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.

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Title: FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
Authors: Zaghdoudi S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Decaup E; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Belhabib I; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Samain R; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Cassant-Sourdy S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Rochotte J; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Brunel A; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Schlaepfer D; Department of Reproductive Medicine Moores Cancer Center, University of California San Diego, La Jolla, CA, USA., Cros J; Department of Pathology, Beaujon Hospital, INSERM U1149, Clichy, France., Neuzillet C; Medical Oncology Department, Curie Institute, Versailles Saint-Quentin University, Saint-Cloud, France., Strehaiano M; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Alard A; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Tomasini R; Cancer Research Center of Marseille, INSERM U1068, Marseille, France., Rajeeve V; Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK., Perraud A; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France., Mathonnet M; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France., Pearce OM; Centre for Tumour Microenvironment, Barts Cancer Institute, London, UK., Martineau Y; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Pyronnet S; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Bousquet C; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France., Jean C; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.
Source: EMBO molecular medicine [EMBO Mol Med] 2020 Nov 06; Vol. 12 (11), pp. e12010. Date of Electronic Publication: 2020 Oct 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
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  Data: <searchLink fieldCode="AU" term="%22Zaghdoudi+S%22">Zaghdoudi S</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Decaup+E%22">Decaup E</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Belhabib+I%22">Belhabib I</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Samain+R%22">Samain R</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Cassant-Sourdy+S%22">Cassant-Sourdy S</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Rochotte+J%22">Rochotte J</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Brunel+A%22">Brunel A</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Schlaepfer+D%22">Schlaepfer D</searchLink>; Department of Reproductive Medicine Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cros+J%22">Cros J</searchLink>; Department of Pathology, Beaujon Hospital, INSERM U1149, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Neuzillet+C%22">Neuzillet C</searchLink>; Medical Oncology Department, Curie Institute, Versailles Saint-Quentin University, Saint-Cloud, France.<br /><searchLink fieldCode="AU" term="%22Strehaiano+M%22">Strehaiano M</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Alard+A%22">Alard A</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Tomasini+R%22">Tomasini R</searchLink>; Cancer Research Center of Marseille, INSERM U1068, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Rajeeve+V%22">Rajeeve V</searchLink>; Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Perraud+A%22">Perraud A</searchLink>; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Mathonnet+M%22">Mathonnet M</searchLink>; EA 3842 Laboratory, Medicine and Pharmacy Faculties, Limoges University, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Pearce+OM%22">Pearce OM</searchLink>; Centre for Tumour Microenvironment, Barts Cancer Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Martineau+Y%22">Martineau Y</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Pyronnet+S%22">Pyronnet S</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bousquet+C%22">Bousquet C</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Jean+C%22">Jean C</searchLink>; Cancer Research Center of Toulouse (CRCT), team 6 'Protein synthesis & secretion in carcinogenesis', Equipe labellisée Ligue Contre Le Cancer, Labex TOUCAN, INSERM UMR 1037- University Toulouse III Paul Sabatier, Toulouse, France.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2020 Nov 06; Vol. 12 (11), pp. e12010. <i>Date of Electronic Publication: </i>2020 Oct 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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