Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.
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| Title: | Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells. |
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| Authors: | Møller TC; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. thor.moller@sund.ku.dk., Pedersen MF; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., van Senten JR; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Seiersen SD; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Mathiesen JM; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Bouvier M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada., Bräuner-Osborne H; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. hbo@sund.ku.dk. |
| Source: | Scientific reports [Sci Rep] 2020 Oct 15; Vol. 10 (1), pp. 17395. Date of Electronic Publication: 2020 Oct 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-020-73674-0 |
