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Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

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Title: Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.
Authors: Møller TC; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. thor.moller@sund.ku.dk., Pedersen MF; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., van Senten JR; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Seiersen SD; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Mathiesen JM; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark., Bouvier M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada., Bräuner-Osborne H; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. hbo@sund.ku.dk.
Source: Scientific reports [Sci Rep] 2020 Oct 15; Vol. 10 (1), pp. 17395. Date of Electronic Publication: 2020 Oct 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Møller+TC%22">Møller TC</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. thor.moller@sund.ku.dk.<br /><searchLink fieldCode="AU" term="%22Pedersen+MF%22">Pedersen MF</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22van+Senten+JR%22">van Senten JR</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Seiersen+SD%22">Seiersen SD</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Mathiesen+JM%22">Mathiesen JM</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bouvier+M%22">Bouvier M</searchLink>; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Bräuner-Osborne+H%22">Bräuner-Osborne H</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, 2100, Copenhagen, Denmark. hbo@sund.ku.dk.
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