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Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure.

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Title: Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure.
Authors: Cibi DM; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Bi-Lin KW; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Shekeran SG; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Sandireddy R; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Tee N; National Heart Research Institute Singapore, National Heart Center Singapore, Singapore 169609., Singh A; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Wu Y; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594., Srinivasan DK; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594., Kovalik JP; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Ghosh S; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857., Seale P; Institute for Diabetes, Obesity, and Metabolism, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA., Singh MK; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore 169857; National Heart Research Institute Singapore, National Heart Center Singapore, Singapore 169609. Electronic address: manvendra.singh@duke-nus.edu.sg.
Source: Cell reports [Cell Rep] 2020 Oct 20; Vol. 33 (3), pp. 108288.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2020.108288