SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.

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Title: SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.
Authors: Sasaki Y; Department of Genetics, Washington University School of Medicine, St. Louis, United States., Kakita H; Department of Genetics, Washington University School of Medicine, St. Louis, United States.; Department of Perinatal and Neonatal Medicine, Aichi Medical University, Aichi, Japan., Kubota S; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Sene A; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Lee TJ; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Ban N; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Dong Z; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Lin JB; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States., Boye SL; Department of Pediatrics, Powell Gene Therapy Center, Gainesville, United States., DiAntonio A; Department of Developmental Biology, Washington University School of Medicine, St. Louis, United States.; Needleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, United States., Boye SE; Department of Pediatrics, Division of Cellular and Molecular Therapy, Gainesville, United States., Apte RS; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, United States.; Department of Developmental Biology, Washington University School of Medicine, St. Louis, United States.; Department of Medicine, Washington University School of Medicine, St. Louis, United States., Milbrandt J; Department of Genetics, Washington University School of Medicine, St. Louis, United States.; Needleman Center for Neurometabolism and Axonal Therapeutics, St. Louis, United States.
Source: ELife [Elife] 2020 Oct 27; Vol. 9. Date of Electronic Publication: 2020 Oct 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.62027