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Identification of preferred multimodal ligand-binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations.

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Title: Identification of preferred multimodal ligand-binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations.
Authors: Gudhka RB; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA., Bilodeau CL; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA., McCallum SA; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA., McCoy MA; Biologics and Vaccines, Downstream Purification Development and Engineering, Merck & Co., Inc., Kenilworth, New Jersey, USA., Roush DJ; Biologics and Vaccines, Downstream Purification Development and Engineering, Merck & Co., Inc., Kenilworth, New Jersey, USA., Snyder MA; Process Chromatography Division, Bio-Rad Laboratories, Hercules, California, USA., Cramer SM; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
Source: Biotechnology and bioengineering [Biotechnol Bioeng] 2021 Feb; Vol. 118 (2), pp. 809-822. Date of Electronic Publication: 2020 Nov 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of preferred multimodal ligand-binding regions on IgG1 F<subscript>C</subscript> using nuclear magnetic resonance and molecular dynamics simulations.
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  Data: <searchLink fieldCode="AU" term="%22Gudhka+RB%22">Gudhka RB</searchLink>; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bilodeau+CL%22">Bilodeau CL</searchLink>; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.<br /><searchLink fieldCode="AU" term="%22McCallum+SA%22">McCallum SA</searchLink>; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.<br /><searchLink fieldCode="AU" term="%22McCoy+MA%22">McCoy MA</searchLink>; Biologics and Vaccines, Downstream Purification Development and Engineering, Merck & Co., Inc., Kenilworth, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Roush+DJ%22">Roush DJ</searchLink>; Biologics and Vaccines, Downstream Purification Development and Engineering, Merck & Co., Inc., Kenilworth, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Snyder+MA%22">Snyder MA</searchLink>; Process Chromatography Division, Bio-Rad Laboratories, Hercules, California, USA.<br /><searchLink fieldCode="AU" term="%22Cramer+SM%22">Cramer SM</searchLink>; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.; Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
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              Text: 2021 Feb
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