Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
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| Title: | Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis. |
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| Authors: | Bakalov V; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.; Medicine Institute, Allegheny Health Network, Pittsburgh, PA, United States of America., Reyes-Uribe L; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America., Deshpande R; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States of America., Maloy AL; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America., Shapiro SD; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America., Angus DC; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America., Chang CH; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America., Le Moyec L; Université d'Evry Val d'Essonne-Université Paris-Saclay, Evry, France.; Muséum National d'Histoire Naturelle, Unité MCAM, UMR7245 CNRS, Paris, France., Wendell SG; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States of America., Kaynar AM; Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.; Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America. |
| Source: | PloS one [PLoS One] 2020 Nov 05; Vol. 15 (11), pp. e0241122. Date of Electronic Publication: 2020 Nov 05 (Print Publication: 2020). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0241122 |