Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma.
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| Title: | Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma. |
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| Authors: | Lu D; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA. lu.dan@gene.com.; Genentech Research and Early Development, 1 DNA Way, MS46-3a, South San Francisco, California, 94080, USA. lu.dan@gene.com., Lu T; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Shi R; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Gibiansky L; QuantPharm LLC, North Potomac, Maryland, USA., Agarwal P; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Shemesh CS; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Dere RC; Department of Bioanalytical Sciences, Genentech, Inc, South San Francisco, California, USA., Ogbu U; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA., Hirata J; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA., Chanu P; Department of Clinical Pharmacology, Genentech, Inc/F. Hoffmann-La Roche Ltd, Lyon, France., Girish S; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Jin JY; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Li C; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Miles D; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA. |
| Source: | Pharmaceutical research [Pharm Res] 2020 Dec 01; Vol. 37 (12), pp. 252. Date of Electronic Publication: 2020 Dec 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-904X |
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| DOI: | 10.1007/s11095-020-02933-6 |