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Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma.

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Title: Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma.
Authors: Lu D; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA. lu.dan@gene.com.; Genentech Research and Early Development, 1 DNA Way, MS46-3a, South San Francisco, California, 94080, USA. lu.dan@gene.com., Lu T; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Shi R; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Gibiansky L; QuantPharm LLC, North Potomac, Maryland, USA., Agarwal P; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Shemesh CS; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Dere RC; Department of Bioanalytical Sciences, Genentech, Inc, South San Francisco, California, USA., Ogbu U; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA., Hirata J; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA., Chanu P; Department of Clinical Pharmacology, Genentech, Inc/F. Hoffmann-La Roche Ltd, Lyon, France., Girish S; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Jin JY; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Li C; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Miles D; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.
Source: Pharmaceutical research [Pharm Res] 2020 Dec 01; Vol. 37 (12), pp. 252. Date of Electronic Publication: 2020 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lu+D%22">Lu D</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA. lu.dan@gene.com.; Genentech Research and Early Development, 1 DNA Way, MS46-3a, South San Francisco, California, 94080, USA. lu.dan@gene.com.<br /><searchLink fieldCode="AU" term="%22Lu+T%22">Lu T</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Shi+R%22">Shi R</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Gibiansky+L%22">Gibiansky L</searchLink>; QuantPharm LLC, North Potomac, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Agarwal+P%22">Agarwal P</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Shemesh+CS%22">Shemesh CS</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Dere+RC%22">Dere RC</searchLink>; Department of Bioanalytical Sciences, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Ogbu+U%22">Ogbu U</searchLink>; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Hirata+J%22">Hirata J</searchLink>; Product Development Oncology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Chanu+P%22">Chanu P</searchLink>; Department of Clinical Pharmacology, Genentech, Inc/F. Hoffmann-La Roche Ltd, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Girish+S%22">Girish S</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Jin+JY%22">Jin JY</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Miles+D%22">Miles D</searchLink>; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.
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