Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling.
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| Title: | Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling. |
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| Authors: | Mendu SK; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Stremska ME; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA., Schappe MS; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Moser EK; University of Florida, Gainesville, FL 32610, USA., Krupa JK; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Rogers JS; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Stipes EJ; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Parker CA; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA., Braciale TJ; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA., Perry JSA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, NY 10065, USA., Desai BN; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA. bdesai@virginia.edu.; Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA.; Robert M. Berne Cardiovascular Research Center, Charlottesville, VA 22908, USA. |
| Source: | Science signaling [Sci Signal] 2020 Dec 08; Vol. 13 (661). Date of Electronic Publication: 2020 Dec 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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