Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection.
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| Title: | Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection. |
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| Authors: | Li X; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA. jwang@crystal.harvard.edu ellis_reinherz@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Mizsei R; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA. jwang@crystal.harvard.edu ellis_reinherz@dfci.harvard.edu., Tan K; Structural Biology Center, X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Lemont, IL, USA., Mallis RJ; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Dermatology, Harvard Medical School, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Duke-Cohan JS; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Akitsu A; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Tetteh PW; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Dubey A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Hwang W; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Department of Materials Science & Engineering, Texas A&M University, College Station, TX, USA.; Department of Physics & Astronomy, Texas A&M University, College Station, TX, USA.; School of Computational Sciences, Korea Institute for Advanced Study, Seoul, Republic of Korea., Wagner G; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Lang MJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Arthanari H; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Wang JH; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA. jwang@crystal.harvard.edu ellis_reinherz@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Reinherz EL; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA. jwang@crystal.harvard.edu ellis_reinherz@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA. |
| Source: | Science (New York, N.Y.) [Science] 2021 Jan 08; Vol. 371 (6525), pp. 181-185. Date of Electronic Publication: 2020 Dec 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.abe0918 |
