Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.
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| Title: | Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation. |
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| Authors: | Hamilton JZ; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Pires TA; Department of Chemistry, University of Illinois at Urbana-Champaign, 505 South Mathews Ave., Urbana, IL, 61801, USA., Mitchell JA; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Cochran JH; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Emmerton KK; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Zaval M; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Stone IJ; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Anderson ME; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Jin S; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Waight AB; Protein Sciences, Discovery Biologics, Merck Research Laboratories, 213 E Grand Ave., South San Francisco, CA, 94080, USA., Lyon RP; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Senter PD; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Jeffrey SC; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA., Burke PJ; Seagen Inc., 21823 30th Drive SE, Bothell, WA, 98021, USA. |
| Source: | ChemMedChem [ChemMedChem] 2021 Apr 08; Vol. 16 (7), pp. 1077-1081. Date of Electronic Publication: 2021 Feb 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1860-7187 |
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| DOI: | 10.1002/cmdc.202000889 |
