Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia.
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| Title: | Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia. |
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| Authors: | Cox MJ; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; University of Minnesota Graduate School, Bioinformatics and Computational Biology, Minneapolis, MN, USA., Lucien F; Department of Urology, Mayo Clinic, Rochester, MN, USA., Sakemura R; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Boysen JC; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Kim Y; Department of Urology, Mayo Clinic, Rochester, MN, USA., Horvei P; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Department of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA., Manriquez Roman C; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA., Hansen MJ; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Tapper EE; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Siegler EL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Forsman C; T Cell Engineering, Mayo Clinic, Rochester, MN, USA., Crotts SB; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Schick KJ; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA; Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., Hefazi M; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Ruff MW; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Can I; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA., Adada M; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Bezerra E; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Kankeu Fonkoua LA; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Nevala WK; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Braggio E; Department of Cancer Biology, Mayo Clinic, Phoenix, AZ, USA., Ding W; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Parikh SA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA., Kay NE; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Department of Immunology, Mayo Clinic, Rochester, MN, USA., Kenderian SS; T Cell Engineering, Mayo Clinic, Rochester, MN, USA; Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA; Department of Immunology, Mayo Clinic, Rochester, MN, USA. Electronic address: kenderian.saad@mayo.edu. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Apr 07; Vol. 29 (4), pp. 1529-1540. Date of Electronic Publication: 2021 Jan 01. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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