Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
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| Title: | Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs. |
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| Authors: | Troup RI; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Jeffries B; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Saudain RE; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Georgiou E; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Fish J; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Scott JS; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Chiarparin E; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Fallan C; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Linclau B; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K. |
| Source: | The Journal of organic chemistry [J Org Chem] 2021 Jan 15; Vol. 86 (2), pp. 1882-1900. Date of Electronic Publication: 2021 Jan 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1520-6904 |
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| DOI: | 10.1021/acs.joc.0c02810 |
