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Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.

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Title: Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
Authors: Troup RI; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Jeffries B; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Saudain RE; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Georgiou E; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Fish J; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., Scott JS; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Chiarparin E; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Fallan C; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Linclau B; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.
Source: The Journal of organic chemistry [J Org Chem] 2021 Jan 15; Vol. 86 (2), pp. 1882-1900. Date of Electronic Publication: 2021 Jan 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
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  Data: <searchLink fieldCode="AU" term="%22Troup+RI%22">Troup RI</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Jeffries+B%22">Jeffries B</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Saudain+RE%22">Saudain RE</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Georgiou+E%22">Georgiou E</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Fish+J%22">Fish J</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.<br /><searchLink fieldCode="AU" term="%22Scott+JS%22">Scott JS</searchLink>; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.<br /><searchLink fieldCode="AU" term="%22Chiarparin+E%22">Chiarparin E</searchLink>; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.<br /><searchLink fieldCode="AU" term="%22Fallan+C%22">Fallan C</searchLink>; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K.<br /><searchLink fieldCode="AU" term="%22Linclau+B%22">Linclau B</searchLink>; Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.
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        Value: 10.1021/acs.joc.0c02810
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      – TitleFull: Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
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              Text: 2021 Jan 15
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