Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism.
Saved in:
| Title: | Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism. |
|---|---|
| Authors: | Miyashita SI; Department of Urology, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Surgery and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Zhang J; Department of Urology, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Surgery and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Zhang S; Department of Urology, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Surgery and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Shoemaker CB; Department of Infectious Diseases and Global Health, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA., Dong M; Department of Urology, Boston Children's Hospital, Boston, MA 02115, USA. min.dong@childrens.harvard.edu.; Department of Surgery and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2021 Jan 06; Vol. 13 (575). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1946-6242 |
|---|---|
| DOI: | 10.1126/scitranslmed.aaz4197 |
