The impact of a 1-hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure.

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Title: The impact of a 1-hour time interval between pazopanib and subsequent intake of gastric acid suppressants on pazopanib exposure.
Authors: Krens SD; Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Lubberman FJE; Department of Pharmacy, Ziekenhuis Gelderse Vallei, Ede, The Netherlands., van Egmond M; Department of Clinical Pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands., Jansman FGA; Department of Pharmacy, Deventer Hospital, Deventer, The Netherlands.; PharmacoTherapy, -Epidemiology & -Economics, University of Groningen, Groningen Research Institute of Pharmacy, Groningen, The Netherlands., Burger DM; Department of Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Hamberg P; Department of Medical Oncology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands., Vervenne WL; Department of Medical Oncology, Deventer Hospital, Deventer, The Netherlands., Gelderblom H; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., van der Graaf WTA; Department of Medical Oncology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Desar IME; Department of Medical Oncology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., van Herpen CML; Department of Medical Oncology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., van Erp NP; Department of Clinical Pharmacy, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.
Source: International journal of cancer [Int J Cancer] 2021 Jun 01; Vol. 148 (11), pp. 2799-2806. Date of Electronic Publication: 2021 Jan 19.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1097-0215
DOI:10.1002/ijc.33469