Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting stearoyl-CoA desaturase-1.

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Title: Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting stearoyl-CoA desaturase-1.
Authors: Helder RWJ; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: r.w.j.helder@lacdr.leidenuniv.nl., Rousel J; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: jrousel@chdr.nl., Boiten WA; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: w.a.boiten2@lacdr.leidenuniv.nl., Gooris GS; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: g.gooris@lacdr.leidenuniv.nl., Nadaban A; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: a.nadaban@lacdr.leidenuniv.nl., El Ghalbzouri A; Department of Dermatology, LUMC, Leiden, the Netherlands. Electronic address: a.ghalbzouri@lumc.nl., Bouwstra JA; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands. Electronic address: Bouwstra@lacdr.leidenuniv.nl.
Source: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Apr; Vol. 1866 (4), pp. 158885. Date of Electronic Publication: 2021 Jan 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-2618
DOI:10.1016/j.bbalip.2021.158885