Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.

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Title: Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
Authors: Walker JS; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Hing ZA; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Harrington B; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA., Baumhardt J; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ozer HG; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., Lehman A; Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., Giacopelli B; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Beaver L; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Williams K; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Skinner JN; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Cempre CB; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Sun Q; Department of Pathology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China., Shacham S; Karyopharm Therapeutics Inc, Newton, MA, USA., Stromberg BR; Department of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University, Columbus, OH, USA., Summers MK; Department of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University, Columbus, OH, USA., Abruzzo LV; Department of Pathology, The Ohio State University, Columbus, OH, USA., Rassenti L; Department of Medicine, Division of Hematology, University of California-San Diego School of Medicine, San Diego, CA, USA., Kipps TJ; Department of Medicine, Division of Hematology, University of California-San Diego School of Medicine, San Diego, CA, USA., Parikh S; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA., Kay NE; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA., Rogers KA; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Woyach JA; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Coppola V; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, OH, USA.; Genetically Engineered Mouse Modeling Core, The Ohio State University and Arthur G. James Comprehensive Cancer Center, Columbus, OH, USA., Chook YM; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Oakes C; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA., Byrd JC; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA.; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA., Lapalombella R; Division of Hematology, Department of Internal Medicine, The Ohio State University, 460 OSUCCC, 410 West 12th Avenue, Columbus, OH, 43210, USA. rosa.lapalombella@osumc.edu.
Source: Journal of hematology & oncology [J Hematol Oncol] 2021 Jan 15; Vol. 14 (1), pp. 17. Date of Electronic Publication: 2021 Jan 15.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722 (Electronic) Linking ISSN: 17568722 NLM ISO Abbreviation: J Hematol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1756-8722
DOI:10.1186/s13045-021-01032-2