BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics.

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Title: BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics.
Authors: Hall AP; UCB BioPharma, Slough, United Kingdom., Tepper JS; Tepper Nonclinical Consulting, San Carlos, CA, USA., Boyle MH; 201915Covance Inc., Somerset, NJ, USA., Cary MG; Pathology Experts GmbH, Witterswil, Switzerland., Flandre TG; 98560Novartis Institutes for Biomedical Research, Basel, Switzerland., Piaia A; 98560Novartis Institutes for Biomedical Research, Basel, Switzerland., Tarnow I; Savara Pharmaceuticals, Hørsholm, Denmark., Macri NP; Tepper Nonclinical Consulting, San Carlos, CA, USA., Freke MC; 70294Charles River Laboratories Montreal ULC, Senneville, Quebec, Canada., Nikula KJ; Inotiv, Maryland Heights, MO, USA., Paul GR; 1929GlaxoSmithKline, Ware, United Kingdom., Cauvin A; UCB BioPharma SRL, Braine L'Alleud, Belgium., Gregori M; Covance, Huntingdon, United Kingdom., Haworth R; 1929GlaxoSmithKline, Ware, United Kingdom., Naylor S; Charles River Laboratories, Edinburgh, United Kingdom., Price M; 1929GlaxoSmithKline, Ware, United Kingdom., Robinson IN; 4625AstraZeneca, Melbourn, United Kingdom., Allen A; 18869Chiesi Farmaceutici S.p.A., Parma, Italy., Gelzleichter T; Genentech Inc., South San Francisco, CA, USA., Hohlbaum AM; Sanofi, Zwijnaarde, Belgium., Manetz S; AstraZeneca, Gaithersburg, MD, USA., Wolfreys A; UCB BioPharma, Slough, United Kingdom., Colman K; 70089Genomics Institute for the Novartis Research Foundation, San Diego, CA, USA., Fleurance R; UCB BioPharma SRL, Braine L'Alleud, Belgium., Jones D; 9059MHRA, London, United Kingdom., Mukaratirwa S; Covance, Huntingdon, United Kingdom.
Source: Toxicologic pathology [Toxicol Pathol] 2021 Feb; Vol. 49 (2), pp. 235-260. Date of Electronic Publication: 2021 Jan 18.
Publication Type: Journal Article; Review
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7905907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-1601 (Electronic) Linking ISSN: 01926233 NLM ISO Abbreviation: Toxicol Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1533-1601
DOI:10.1177/0192623320976094