Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.

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Title: Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.
Authors: Cheng Z; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Bethel CR; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA., Thomas PW; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA., Shurina BA; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Alao JP; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Thomas CA; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Yang K; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Marshall SH; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA., Zhang H; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Sturgill AM; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Kravats AN; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu., Page RC; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA., Fast W; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and the LaMontagne Center for Infectious Disease, University of Texas, Austin, Texas, USA., Bonomo RA; Research Services, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (CASE VA CARES), Cleveland, Ohio, USA., Crowder MW; Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA kravatan@miamioh.edu robert.bonomo@va.gov crowdemw@miamioh.edu.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Mar 18; Vol. 65 (4). Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1098-6596
DOI:10.1128/AAC.01714-20